Research Interests

Our main research focuses are:

  • Mechanobiology: how proteins sense physical/chemical changes and regulate vascular and tubular function in health and disease states, such as hemostasis, thrombosis, hemophilia, von Willebrand disease, kidney and lung diseases.
  • Cell adhesion: how protein-protein interactions regulate cell signaling pathways and lead to long/short-range cell-cell interactions
  • Disease modeling and therapeutic method development using iPS cells, gene editing, and organoids

       

Single molecule/cell force spectroscopy               Single molecule/cell fluorescence microscopy